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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 3
2001 4
2002 4
2003 7
2004 3
2005 10
2006 9
2007 8
2008 17
2009 14
2010 9
2011 13
2012 11
2013 16
2014 13
2015 11
2016 8
2017 8
2018 5
2019 9
2020 13
2021 6
2022 4
2023 7
2024 2

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186 results

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Page 1
Diabetic Cardiomyopathy.
Dillmann WH. Dillmann WH. Circ Res. 2019 Apr 12;124(8):1160-1162. doi: 10.1161/CIRCRESAHA.118.314665. Circ Res. 2019. PMID: 30973809 Free PMC article. Review.
Diabetic cardiomyopathy was initially described as a human pathophysiological condition in which heart failure occurred in the absence of coronary artery disease, hypertension, and valvular heart disease. Recent studies in diabetic animal models identify decr …
Diabetic cardiomyopathy was initially described as a human pathophysiological condition in which heart failure occurred in the …
USP25 Ameliorates Pathological Cardiac Hypertrophy by Stabilizing SERCA2a in Cardiomyocytes.
Ye B, Zhou H, Chen Y, Luo W, Lin W, Zhao Y, Han J, Han X, Huang W, Wu G, Wang X, Liang G. Ye B, et al. Circ Res. 2023 Feb 17;132(4):465-480. doi: 10.1161/CIRCRESAHA.122.321849. Epub 2023 Feb 1. Circ Res. 2023. PMID: 36722348
BACKGROUND: Pathological cardiac hypertrophy can lead to heart failure and is one of the leading causes of death globally. Understanding the molecular mechanism of pathological cardiac hypertrophy will contribute to the treatment of heart failure. DUBs …
BACKGROUND: Pathological cardiac hypertrophy can lead to heart failure and is one of the leading causes of death globally. Und …
Gene therapy for heart failure.
Greenberg B. Greenberg B. Trends Cardiovasc Med. 2017 Apr;27(3):216-222. doi: 10.1016/j.tcm.2016.11.001. Epub 2016 Nov 5. Trends Cardiovasc Med. 2017. PMID: 28063800 Review.
Novel strategies are needed to treat the growing population of heart failure patients. While new drug and device based therapies have improved outcomes over the past several decades, heart failure patients continue to experience amongst the lowest qual …
Novel strategies are needed to treat the growing population of heart failure patients. While new drug and device based therapi …
Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.
Angrisano T, Schiattarella GG, Keller S, Pironti G, Florio E, Magliulo F, Bottino R, Pero R, Lembo F, Avvedimento EV, Esposito G, Trimarco B, Chiariotti L, Perrino C. Angrisano T, et al. PLoS One. 2014 Sep 2;9(9):e106024. doi: 10.1371/journal.pone.0106024. eCollection 2014. PLoS One. 2014. PMID: 25181347 Free PMC article.
Re-induction of fetal genes and/or re-expression of postnatal genes represent hallmarks of pathological cardiac remodeling, and are considered important in the progression of the normal heart towards heart failure (HF). Whether epigenetic modifications are in …
Re-induction of fetal genes and/or re-expression of postnatal genes represent hallmarks of pathological cardiac remodeling, and are consider …
Xin-Ji-Er-Kang protects myocardial and renal injury in hypertensive heart failure in mice.
Ling XX, Chen H, Fu BB, Ruan CS, Pana M, Zhou K, Fang ZR, Shao JT, Zhu FQ, Gao S. Ling XX, et al. Phytomedicine. 2021 Oct;91:153675. doi: 10.1016/j.phymed.2021.153675. Epub 2021 Jul 18. Phytomedicine. 2021. PMID: 34332285
HYPOTHESIS/PURPOSE: We investigated the effects of XJEK on cardiovascular- and renal-function in a heart failure mouse model induced by high salt (HS) and the associated mechanisms. STUDY DESIGN: For the purpose of assessing the effects of XJEK on a hypertensive …
HYPOTHESIS/PURPOSE: We investigated the effects of XJEK on cardiovascular- and renal-function in a heart failure mouse model i …
Post-translational Modifications in Heart Failure: Small Changes, Big Impact.
Lee A, Oh JG, Gorski PA, Hajjar RJ, Kho C. Lee A, et al. Heart Lung Circ. 2016 Apr;25(4):319-24. doi: 10.1016/j.hlc.2015.11.008. Epub 2015 Dec 4. Heart Lung Circ. 2016. PMID: 26795636 Free PMC article. Review.
Heart failure is a complex disease process with various aetiologies and is a significant cause of morbidity and death world-wide. ...Small ubiquitin-like modifier mediated modification (SUMOylation) pathway was found to play essential roles in cardiac development an
Heart failure is a complex disease process with various aetiologies and is a significant cause of morbidity and death world-wi
Advances in gene therapy for heart failure.
Fish KM, Ishikawa K. Fish KM, et al. Discov Med. 2015 Apr;19(105):285-91. Discov Med. 2015. PMID: 25977191 Free article. Review.
Chronic heart failure is expected to increase its social and economic burden as a consequence of improved survival in patients with acute cardiac events. Cardiac gene therapy holds significant promise in heart failure treatment for patients with curren …
Chronic heart failure is expected to increase its social and economic burden as a consequence of improved survival in patients …
Darier disease is associated with heart failure: a cross-sectional case-control and population based study.
Bachar-Wikstrom E, Curman P, Ahanian T, Leong IUS, Larsson H, Cederlöf M, Wikstrom JD. Bachar-Wikstrom E, et al. Sci Rep. 2020 Apr 23;10(1):6886. doi: 10.1038/s41598-020-63832-9. Sci Rep. 2020. PMID: 32327688 Free PMC article.
DD subjects showed normal clinical heart phenotype including heart failure markers and ECG. The risk for heart failure was 1.59 (1,16-2,19) times elevated in DD subjects, while no major differences were found in myocardial infarcation or arrhyth …
DD subjects showed normal clinical heart phenotype including heart failure markers and ECG. The risk for heart
Cardiac SERCA2A/B: therapeutic targets for heart failure.
Shareef MA, Anwer LA, Poizat C. Shareef MA, et al. Eur J Pharmacol. 2014 Feb 5;724:1-8. doi: 10.1016/j.ejphar.2013.12.018. Epub 2013 Dec 18. Eur J Pharmacol. 2014. PMID: 24361307 Review.
Among the many SERCA isoforms identified so far, SERCA2a is restricted to slow-twitch skeletal and cardiac muscle, while SERCA2b is ubiquitously expressed. SERCA2a/b expression and activity are altered in major heart diseases such as ischemic heart disease, cardiomy …
Among the many SERCA isoforms identified so far, SERCA2a is restricted to slow-twitch skeletal and cardiac muscle, while SERCA2b is ubiquito …
The function and significance of SERA2a in congestive heart failure: an analysis of gene therapy trials.
Wu P, Zhai Y, Li D. Wu P, et al. Histol Histopathol. 2017 Aug;32(8):767-777. doi: 10.14670/HH-11-878. Epub 2017 Jan 30. Histol Histopathol. 2017. PMID: 28134413 Review.
Congestive heart failure (CHF) is a widespread disease that has a negative impact on health, worldwide. ...
Congestive heart failure (CHF) is a widespread disease that has a negative impact on health, worldwide. ...
186 results